Single Nucleotide Polymorphism in Ag85 Genes of Mycobacterium Tuberculosis Complex: Analysis of 178 Clinical Isolates from China and 13 BCG strains

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Single Nucleotide Polymorphism in Ag85 Genes of Mycobacterium Tuberculosis Complex: Analysis of 178 Clinical Isolates from China and 13 BCG strains

Host immune pressure and associated immune evasion of pathogenic bacteria are key features of host-pathogen co-evolution. Human T-cell epitopes of Mycobacterium tuberculosis (M. tuberculosis) were evolutionarily hyperconserved and thus it was deduced that M. tuberculosis lacks antigenic variation and immune evasion. However, in our previous studies, proteins MPT64, PstS1, Rv0309 and Rv2945c all...

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Single Nucleotide Polymorphism Analysis of Protamine Genes in Infertile Men

Background Single nucleotide polymorphism (SNPs) are considered as one of the underlying causes of male infertility. Proper sperm chromatin packaging which involves replacement of histones with protamines has profound effect on male fertility. Over 20 SNPs have been reported for the protamine 1 and 2. MaterialsAndMethods The aim of this study was to evaluate the frequency of two previously repo...

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single nucleotide polymorphism analysis of protamine genes in infertile men

background: single nucleotide polymorphism (snps) are considered as one of the underlying causes of male infertility. proper sperm chromatin packaging which involves replacement of histones with protamines has profound effect on male fertility. over 20 snps have been reported for the protamine 1 and 2. materials and methods: the aim of this study was to evaluate the frequency of two previously ...

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ژورنال

عنوان ژورنال: International Journal of Medical Sciences

سال: 2015

ISSN: 1449-1907

DOI: 10.7150/ijms.9951